As they are extremely small and delicate, their discovery is quite recent. To better understand the biology and importance of these tiny vesicles, we optimized the super-resolution imaging conditions for living heart cells and acquired fascinating videos of dynamic mitochondria and their derived vesicles. We have recently published both a quantification study of mitochondria-derived vesicles [1] and a Data Descriptor article [2] to make the data easier to reuse for other researchers. The entire dataset is made available for anyone to explore from DataverseNO https://doi.org/10.18710/PDCLAS [3].
References
1. Opstad, I.S., et al., Mitochondrial dynamics and quantification of mitochondria‐derived vesicles in cardiomyoblasts using structured illumination microscopy. Journal of Biophotonics, 2021: p. e202100305.
2. Opstad, I.S., et al., Three-dimensional structured illumination microscopy data of mitochondria and lysosomes in cardiomyoblasts under normal and galactose-adapted conditions. Scientific Data, 2022. 9(1): p. 1-7.
3. Opstad, I.S., 3DSIM data of mitochondria in the cardiomyoblast cell-line H9c2 adapted to either glucose or galactose. 2021: DataverseNO.