Prokaryote Molecular and Synthetic Biology
27 February - 1 March
Registration is closed
The objective of the course is to provide an understanding of the physiology of the microbial cell and how it can be manipulated. In the first part, the focus will be on molecular biology and physiology, emphasizing topics that are important for synthetic biology. The second part focuses on the approaches and tools directly utilized in synthetic biology. For the topics on genetic circuits and -omics technologies, the aim is to provide the students with the understanding of what these approaches may contribute to a project. The student will acquire fundamental knowledge of prokaryote molecular biology and physiology at an advanced level as well as knowledge about recent advances in prokaryote molecular biology. They will also be critically reviewing a published paper.
6-8 February: Basic prokaryote molecular biology and physiology
1.1 Gene expression and regulation
1.2 Growth and Bioenergetics
1.3 Cell differentiation
1.4 Secondary metabolism
1.5 Cell communication and interactions
1.6 Coordination and regulation of microbial metabolism
27 February - 1 March: Synthetic Biology
2.1 Genetic circuits
2.2 Design, construction and expression of synthetic pathways
2.3 Genetic engineering techniques and tool boxes
2.4 Synthetic genomes and gene editing (Crispr/Cas)
2.5 Omics technologies
a. Genomics and transcriptomics
c. Metabolomics, fluxomics, lipid
The course will be given in English. The course material will consist of around 300 pages book chapters, papers and lecture notes. The students will prepare a poster presentation of a given paper for the second week. The grade (passed/not passed) is given based on the poster presentation (20 %) and an exam (80 %).
If you apply close to the deadline 1st of February (later than 10th of January) please contact the course coordinator Helga Ertesvåg in order to get early access to the course materials (firstname.lastname@example.org, tlf +47 73598678). She can also give further information on the course.